Article
Gene function analysis using the chicken B-cell line DT40.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007
Caldwell Randolph B, Fiedler Petra, Schoetz Ulrike, Buerstedde Jean-Marie
Abstract excerpt
Quidquid agis, prudenter agas et respice finem!-Whatever you do, do it wisely and consider the goal. In consideration of that sage advice, the chicken B-cell line DT40 is an excellent model cell system to study the function of vertebrate genes. In addition to being highly amenable to gene manipulations, the recent influx of genome and gene/protein resources allows for the straightforward selection, design, and...
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