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Establishment of the DNA repair-defective mutants in DT40 cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012

Ishiai Masamichi, Uchida Emi, Takata Minoru

Abstract excerpt

The chicken B cell line DT40 has been widely used as a model system for reverse genetics studies in higher eukaryotes, because of its advantages including efficient gene targeting and ease of chromosome manipulation. Although the genetic approach using the RNA interference technique has become the standard method particularly in human cells, DT40 still remains a powerful tool to investigate the regulation and...

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PMID: 22941595
DOI: 10.1007/978-1-61779-998-3_4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Establishment of the DNA repair-defective mutants in DT40 cells.PMID 22941595Read ↗

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