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Article

Widespread hyperplasia induced by transgenic TGFalpha in ApcMin mice is associated with only regional effects on tumorigenesis.

Carcinogenesis - 1 Sept 2008

Bilger Andrea, Sullivan Ruth, Prunuske Amy J, Clipson Linda, Drinkwater Norman R, Dove William F

Abstract excerpt

Using a mouse predisposed to neoplasia by a germ line mutation in Apc (Apc(Min)), we tested whether induced hyperplasia is sufficient to increase intestinal tumor multiplicity or size in the intestine. We found that hyperplasia in the jejunum correlated with a significant increase in tumor multip...

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Identifiers

PMID: 18310091
DOI: 10.1093/carcin/bgn038
PMCID: PMC2547353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18310091-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Widespread hyperplasia induced by transgenic TGFalpha in ApcMin mice is associated with only regional effects on tumorigenesis.PMID 18310091Read ↗

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