Frequency and histological appearance of adenomas in multiple intestinal neoplasia mice are unaffected by severe combined immunodeficiency (scid) mutation.

doi:10.1002/(SICI)1097-0215(19960117)65:2<249::AID-IJC20>3.0.CO;2-7

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Article

Frequency and histological appearance of adenomas in multiple intestinal neoplasia mice are unaffected by severe combined immunodeficiency (scid) mutation.

International journal of cancer - 17 Jan 1996

Dudley M E, Sundberg J P, Roopenian D C

Abstract excerpt

Well-characterized murine mutations are powerful analytical tools for the genetic analysis of tumorigenesis. We crossed the multiple intestinal neoplasia (Min) allele of adenomatous polyposis coli (Apc), which produces a profound pre-disposition to intestinal neoplasia, with the severe combined i...

Topics

Adenomatous Polyposis Coli
Alleles
Animals
DNA Repair
Intestinal Neoplasms
Mice
Mice, SCID
Mutation
Phenotype

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