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Article

AMPK: An Epigenetic Landscape Modulator

19 Oct 2018

Abstract excerpt

Activated by AMP-dependent and -independent mechanisms, AMP-activated protein kinase (AMPK) plays a central role in the regulation of cellular bioenergetics and cellular survival. AMPK regulates a diverse set of signaling networks that converge to epigenetically mediate transcriptional events. Reversible histone and DNA modifications, such as acetylation and methylation, result in structural chromatin alterations...

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PMID: 30347687
DOI: 10.3390/ijms19103238

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