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Article

Antithrombin up-regulates AMP-activated protein kinase signalling during myocardial ischaemia/reperfusion injury.

Thrombosis and haemostasis - 1 Feb 2015

Ma Yina, Wang Jinli, Gao Junjie, Yang Hui, Wang Yanqing, Manithody Chandrashekhara, Li Ji, Rezaie Alireza R

Abstract excerpt

Antithrombin (AT) is a protein of the serpin superfamily involved in regulation of the proteolytic activity of the serine proteases of the coagulation system. AT is known to exhibit anti-inflammatory and cardioprotective properties when it binds to heparan sulfate proteoglycans (HSPGs) on vascular cells. AMP-activated protein kinase (AMPK) plays an important cardioprotective role during myocardial ischaemia and...

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Identifiers

PMID: 25230600
DOI: 10.1160/TH14-04-0360
PMCID: PMC4308562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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