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Article

Targeting AMPK for cardiac protection: opportunities and challenges.

Journal of molecular and cellular cardiology - 1 Oct 2011

Kim Maengjo, Tian Rong

Abstract excerpt

AMP-activated protein kinase (AMPK) regulates cellular energy homeostasis and multiple biological processes in cell growth and survival, hence an attractive drug target. AMPK is a heterotrimeric protein consisting of α catalytic, β and γ regulatory subunits; two isoforms of each subunit are present in the heart. Studies using both genetic and pharmacological approaches have demonstrated important roles of AMPK in...

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Identifiers

PMID: 21147121
DOI: 10.1016/j.yjmcc.2010.12.004
PMCID: PMC3078514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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