Article
Microarray expression analysis in delayed cardioprotection: the effect of exercise, AICAR, or metformin and the possible role of AMP-activated protein kinase (AMPK).
Molecular and cellular biochemistry - 1 Jan 2012
Solskov Lasse, Magnusson Nils E, Kristiansen Steen B, Jessen Niels, Nielsen Torsten T, Schmitz Ole, Bøtker Hans Erik, Lund Sten
Abstract excerpt
AMP-activated protein kinase (AMPK) is an enzyme which may be involved in cardioprotective mechanisms in the ischemic heart. Exercise, AICAR, and metformin, all known activators of AMPK, induce delayed cardioprotection which protects the heart against ischemia-reperfusion injury. The objective wa...
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