Article
The mechanism of the reverse recovery step, phosphate release, and actin activation of Dictyostelium myosin II.
The Journal of biological chemistry - 28 Mar 2008
Gyimesi Máté, Kintses Bálint, Bodor Andrea, Perczel András, Fischer Stefan, Bagshaw Clive R, Málnási-Csizmadia András
Abstract excerpt
The rate-limiting step of the myosin basal ATPase (i.e. in absence of actin) is assumed to be a post-hydrolysis swinging of the lever arm (reverse recovery step), that limits the subsequent rapid product release steps. However, direct experimental evidence for this assignment is lacking. To inves...
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