Article
Dynamics of actomyosin interactions in relation to the cross-bridge cycle.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Dec 2004
Zeng Wei, Conibear Paul B, Dickens Jane L, Cowie Ruth A, Wakelin Stuart, Málnási-Csizmadia András, Bagshaw Clive R
Abstract excerpt
Transient kinetic measurements of the actomyosin ATPase provided the basis of the Lymn-Taylor model for the cross-bridge cycle, which underpins current models of contraction. Following the determination of the structure of the myosin motor domain, it has been possible to introduce probes at defined sites and resolve the steps in more detail. Probes have been introduced in the Dicytostelium myosin II motor domain...
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