Article

New paradigms in actomyosin energy transduction: critical evaluation of non-traditional models for orthophosphate release

2023-04-13

Abstract excerpt

Release of the ATP hydrolysis product inorganic phosphate (Pi) from the active site of myosin is central in chemo-mechanical energy transduction and closely associated with the main force-generating structural change, the power-stroke. Despite intense investigations, the relative timing between Pi-release and the power-stroke remains poorly understood. This hampers in depth understanding of the production of force...

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Literature Corpus work: ec1697d9-031a-59fb-a887-700e7f1cec26
DOI: 10.1101/2023.04.12.535196

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