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Article

Kinetic characterization of the function of myosin loop 4 in the actin-myosin interaction.

Biochemistry - 8 Jan 2008

Gyimesi Maté, Tsaturyan Andrey K, Kellermayer Miklós S Z, Málnási-Csizmadia András

Abstract excerpt

Myosin interacts with actin during its enzymatic cycle, and actin stimulates myosin's ATPase activity. There are extensive interaction surfaces on both actin and myosin. Several surface loops of myosin play different roles in actomyosin interaction. However, the functional role of loop 4 in actin binding is still ambiguous. We explored the role of loop 4 by either mutating its conserved acidic group, Glu-365, to...

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Identifiers

PMID: 18067324
DOI: 10.1021/bi701554a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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