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Article

Structural mechanism of the recovery stroke in the myosin molecular motor.

Proceedings of the National Academy of Sciences of the United States of America - 10 May 2005

Fischer Stefan, Windshügel Björn, Horak Daniel, Holmes Kenneth C, Smith Jeremy C

Abstract excerpt

The power stroke pulling myosin along actin filaments during muscle contraction is achieved by a large rotation ( approximately 60 degrees ) of the myosin lever arm after ATP hydrolysis. Upon binding the next ATP, myosin dissociates from actin, but its ATPase site is still partially open and catalytically off. Myosin must then close and activate its ATPase site while returning the lever arm for the next power...

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Identifiers

PMID: 15863618
DOI: 10.1073/pnas.0408784102
PMCID: PMC1100758

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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