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Article

Two-stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous variants in the MST1R gene and Crohn's disease.

Inflammatory bowel diseases - 1 Apr 2008

Beckly John B, Hancock Laura, Geremia Alessandra, Cummings J R Fraser, Morris Andrew, Cooney Rachel, Pathan Saad, Guo Changcun, Jewell Derek P

Abstract excerpt

BACKGROUND: Genomewide linkage studies identified chromosome 3p21 as an IBD locus. Genomewide association studies have supported this locus and the Wellcome Trust Case Control Consortium (WTCCC) study narrowed it to a 0.6 Mb region. Our objectives were to perform a 2-stage candidate gene association study of the 3p locus and to identify linkage disequilibrium (LD) between significant single-nucleotide...

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PMID: 18200509
DOI: 10.1002/ibd.20365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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