Article
Association analysis of 3p21 with Crohn's disease in a New Zealand population.
Human immunology - 1 Jun 2010
Morgan Angharad R, Han Dug-Yeo, Lam Wen-jiun, Fraser Alan G, Ferguson Lynnette R
Abstract excerpt
Recent genome-wide association studies have provided evidence for the involvement of 3p21 in the pathogenesis of Crohn's disease (CD). Here we attempted to validate the 3p21 region in a well characterized CD case-control New Zealand dataset of 329 CD patients and 521 controls by genotyping tagging single nucleotide polymorphisms (SNPs) across this region. Analysis revealed significant differences between patients...
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