Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.

doi:10.1073/pnas.0706645104

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Article

Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.

Proceedings of the National Academy of Sciences of the United States of America - 11 Sept 2007

Raelson John V, Little Randall D, Ruether Andreas, Fournier Hélène, Paquin Bruno, Van Eerdewegh Paul, Bradley W E C, Croteau Pascal, Nguyen-Huu Quynh, Segal Jonathan, Debrus Sophie, Allard René, Rosenstiel Philip, Franke Andre, Jacobs Gunnar, Nikolaus Susanna, Vidal Jean-Michel, Szego Peter, Laplante Nathalie, Clark Hilary F, Paulussen René J, Hooper John W, Keith Tim P, Belouchi Abdelmajid, Schreiber Stefan

Abstract excerpt

Genome-wide association (GWA) studies offer a powerful unbiased method for the identification of multiple susceptibility genes for complex diseases. Here we report the results of a GWA study for Crohn's disease (CD) using family trios from the Quebec Founder Population (QFP). Haplotype-based association analyses identified multiple regions associated with the disease that met the criteria for genome-wide...

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PMID: 17804789
DOI: 10.1073/pnas.0706645104
PMCID: PMC1965486

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JAKMIP1
NOD2

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