Article
Estrogen receptors alpha and beta and the risk of open-angle glaucoma: the Rotterdam Study.
Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Jan 2008
de Voogd Simone, Wolfs Roger C W, Jansonius Nomdo M, Uitterlinden André G, Pols Huibert A P, Hofman Albert, de Jong Paulus T V M
Abstract excerpt
OBJECTIVE: To investigate whether polymorphisms in the estrogen receptor alpha (ESR1) and beta (ESR2) genes were a risk factor for open-angle glaucoma (OAG). METHODS: Participants 55 years and older from the population-based Rotterdam Study underwent, at baseline and at follow-up, the same ophthalmic examination, including visual field screening and stereo optic disc photography. A diagnosis of OAG was based on...
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