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Article

Polymorphism of beta-adrenergic receptors and susceptibility to open-angle glaucoma.

Molecular vision - 12 Jun 2006

Inagaki Yoko, Mashima Yukihiko, Fuse Nobuo, Funayama Tomoyo, Ohtake Yuichiro, Yasuda Noriko, Murakami Akira, Hotta Yoshihiro, Fukuchi Takeo, Tsubota Kazuo

Abstract excerpt

PURPOSE: The human trabecular meshwork and ciliary body, which express beta-adrenergic receptors (ADRB1 and ADRB2), control aqueous humor dynamics. We investigated associations of ADRB polymorphisms with open-angle glaucoma (OAG), because ADRB gene polymorphisms alter receptor function. METHODS: We studied 240 Japanese controls and 505 Japanese OAG patients including 211 with primary open-angle glaucoma (POAG),...

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Source

Identifiers

PMID: 16785856

Genes

ADRB2
ADRB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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