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Article

Higher testosterone is associated with open-angle glaucoma in women: a genetic predisposition?

Biology of sex differences - 9 May 2023

Vergroesen Joëlle E, Kaynak Adem, Aribas Elif, Kavousi Maryam, van Meurs Joyce B J, Klaver Caroline C W, Ramdas Wishal D

Abstract excerpt

BACKGROUND: Testosterone may be a possible modifiable risk factor for open-angle glaucoma (OAG) and intraocular pressure (IOP), but evidence has been scarce and conflicting. In this study we evaluated the association of testosterone and its genetic predisposition with incident (i) OAG, IOP, retinal nerve fiber layer (RNFL), and ganglion cell-inner plexiform layer (GCL +). METHODS: Participants aged 45-100 years...

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Identifiers

PMID: 37161452
DOI: 10.1186/s13293-023-00512-z
PMCID: PMC10170716

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