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Article

Female-Specific Association between the Apolipoprotein E E4 Allele and Age at Diagnosis of Glaucoma in UK Biobank.

Ophthalmology. Glaucoma - 1 Jan 2025

Shi Yan, Hu Junming, Liu William, Qiu Wei Qiao, He Xinyue, Zhang Miao, Gao Yan, Zhang Xiaoling, Fan Zhigang

Abstract excerpt

OBJECTIVE: To explore the impact of the apolipoprotein E (APOE) E4 allele in the gender-specific aging process in glaucoma by illustrating the interaction between risk factors, including the APOE E4 allele, gender, and intraocular pressure (IOP), for age at diagnosis (AAD) of glaucoma. DESIGN: A cross-sectional study included UK Biobank participants with complete data (2006-2010) for analysis. Data were analyzed...

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Identifiers

PMID: 39097094
DOI: 10.1016/j.ogla.2024.07.009

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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