Estrogen pathway polymorphisms in relation to primary open angle glaucoma: an analysis accounting for gender from the United States.

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Article

Estrogen pathway polymorphisms in relation to primary open angle glaucoma: an analysis accounting for gender from the United States.

Molecular vision - 1 Jan 2013

Pasquale Louis R, Loomis Stephanie J, Weinreb Robert N, Kang Jae H, Yaspan Brian L, Bailey Jessica Cooke, Gaasterland Douglas, Gaasterland Terry, Lee Richard K, Scott William K, Lichter Paul R, Budenz Donald L, Liu Yutao, Realini Tony, Friedman David S, McCarty Catherine A, Moroi Sayoko E, Olson Lana, Schuman Joel S, Singh Kuldev, Vollrath Douglas, Wollstein Gadi, Zack Donald J, Brilliant Murray, Sit Arthur J, Christen William G, Fingert John, Kraft Peter, Zhang Kang, Allingham R Rand, Pericak-Vance Margaret A, Richards Julia E, Hauser Michael A, Haines Jonathan L, Wiggs Janey L

Abstract excerpt

PURPOSE: Circulating estrogen levels are relevant in glaucoma phenotypic traits. We assessed the association between an estrogen metabolism single nucleotide polymorphism (SNP) panel in relation to primary open angle glaucoma (POAG), accounting for gender. METHODS: We included 3,108 POAG cases an...

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PMID: 23869166
PMCID: PMC3712669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23869166-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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