Estrogen receptor beta gene polymorphism and intraocular pressure elevation in female patients with primary open-angle glaucoma.

doi:10.1016/j.ajo.2009.12.030

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Article

Estrogen receptor beta gene polymorphism and intraocular pressure elevation in female patients with primary open-angle glaucoma.

American journal of ophthalmology - 1 May 2010

Mabuchi Fumihiko, Sakurada Yoichi, Kashiwagi Kenji, Yamagata Zentaro, Iijima Hiroyuki, Tsukahara Shigeo

Abstract excerpt

PURPOSE: To assess whether the genetic polymorphisms of estrogen receptor beta (ESR2) are associated with primary open-angle glaucoma (POAG). DESIGN: Case-control study. METHODS: Four hundred and twenty-five Japanese patients with POAG, including normal-tension glaucoma (NTG, n = 213) and high-tension glaucoma (HTG, n = 212), and 191 control subjects without glaucoma were analyzed for polymorphisms of rs1256031...

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Identifiers

PMID: 20399928
DOI: 10.1016/j.ajo.2009.12.030

Genes

ESR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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