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Article

Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants.

Developmental biology - 15 Feb 2008

Sullivan-Brown Jessica, Schottenfeld Jodi, Okabe Noriko, Hostetter Christine L, Serluca Fabrizio C, Thiberge Stephan Y, Burdine Rebecca D

Abstract excerpt

Zebrafish are an attractive model for studying the earliest cellular defects occurring during renal cyst formation because its kidney (the pronephros) is simple and genes that cause cystic kidney diseases (CKD) in humans, cause pronephric dilations in zebrafish. By comparing phenotypes in three d...

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Identifiers

PMID: 18178183
DOI: 10.1016/j.ydbio.2007.11.025
PMCID: PMC2453220

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18178183-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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