Article
From the radiologic pathology archives: pediatric polycystic kidney disease and other ciliopathies: radiologic-pathologic correlation.
Radiographics : a review publication of the Radiological Society of North America, Inc - 1 Jan 2000
Chung Ellen M, Conran Richard M, Schroeder Jason W, Rohena-Quinquilla Ivan R, Rooks Veronica J
Abstract excerpt
Genetic defects of cilia cause a wide range of diseases, collectively known as ciliopathies. Primary, or nonmotile, cilia function as sensory organelles involved in the regulation of cell growth, differentiation, and homeostasis. Cilia are present in nearly every cell in the body and mutations of genes encoding ciliary proteins affect multiple organs, including the kidneys, liver, pancreas, retina, central...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.