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Article

LRRC50, a conserved ciliary protein implicated in polycystic kidney disease.

Journal of the American Society of Nephrology : JASN - 1 Jun 2008

van Rooijen Ellen, Giles Rachel H, Voest Emile E, van Rooijen Carina, Schulte-Merker Stefan, van Eeden Freek J

Abstract excerpt

Cilia perform essential motile and sensory functions central to many developmental and physiological processes. Disruption of their structure or function can have profound phenotypic consequences, and has been linked to left-right patterning and polycystic kidney disease. In a forward genetic screen for mutations affecting ciliary motility, we isolated zebrafish mutant hu255H. The mutation was found to disrupt an...

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PMID: 18385425
DOI: 10.1681/ASN.2007080917
PMCID: PMC2396934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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