Article
Using zebrafish to study the function of nephronophthisis and related ciliopathy genes
2018-12-03
Abstract excerpt
Zebrafish are a valuable vertebrate model in which to study development and characterize genes involved in cystic kidney disease. Zebrafish embryos and larvae are transparent, allowing non-invasive imaging during their rapid development, which takes place over the first 72 hours post fertilisation. Gene-specific knockdown of nephronophthisis-associated genes leads to ciliary phenotypes which can be assessed in var...
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Identifiers and source
- Literature Corpus work
- a3a7cd75-21f8-522a-99e6-58490fcce91a
- DOI
- 10.12688/f1000research.15511.2