Article
Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function.
Development (Cambridge, England) - 1 Dec 1998
Drummond I A, Majumdar A, Hentschel H, Elger M, Solnica-Krezel L, Schier A F, Neuhauss S C, Stemple D L, Zwartkruis F, Rangini Z, Driever W, Fishman M C
Abstract excerpt
The zebrafish pronephric kidney provides a simplified model of nephron development and epithelial cell differentiation which is amenable to genetic analysis. The pronephros consists of two nephrons with fused glomeruli and paired pronephric tubules and ducts. Nephron formation occurs after the di...
Topics
- Animals
- Crosses, Genetic
- DNA-Binding Proteins
- Embryo, Nonmammalian
- Embryonic Induction
- Female
- Gene Expression Regulation, Developmental
- Kidney
- Kidney Glomerulus
- Kidney Tubules
- Male
- Mutagenesis
- Nephrons
- PAX2 Transcription Factor