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Article

Association of yeast Upf1p with direct substrates of the NMD pathway.

Proceedings of the National Academy of Sciences of the United States of America - 26 Dec 2007

Johansson Marcus J O, He Feng, Spatrick Phyllis, Li Chunfang, Jacobson Allan

Abstract excerpt

Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism that detects and degrades transcripts containing premature translation termination codons. Gene expression profiling experiments have shown that inactivation of the NMD pathway leads to the accumulation of both aberrant, nonsense-containing mRNAs, and many apparently wild-type transcripts. Such increases in transcript steady-state levels could arise...

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Identifiers

PMID: 18087042
DOI: 10.1073/pnas.0709257105
PMCID: PMC2409234

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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