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Article

The role of nonsense-mediated mRNA decay in restricting long noncoding RNA expression has been conserved in RNAi-capable budding yeast.

RNA (New York, N.Y.) - 17 Nov 2025

Wery Maxime, Szachnowski Ugo, Creux Constance, Fouilleul Quentin, Lefrere Marina, Morillon Antonin

Abstract excerpt

In most eukaryotes, sense/antisense RNA duplexes can be processed into small interfering RNAs by the ribonuclease III Dicer, a key component of the RNA interference (RNAi) machinery, which has been lost by the budding yeast Saccharomyces cerevisiae Previous studies in this species revealed the pervasive formation of double-stranded (ds) RNA involving antisense Xrn1-sensitive long noncoding (lnc) RNAs, which...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41027714
DOI: 10.1261/rna.080458.125
PMCID: PMC12621597

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