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Article

Association of lipin 1 gene polymorphisms with measures of energy and glucose metabolism.

Obesity (Silver Spring, Md.) - 1 Nov 2007

Loos Ruth J F, Rankinen Tuomo, Pérusse Louis, Tremblay Angelo, Després Jean-Pierre, Bouchard Claude

Abstract excerpt

OBJECTIVE: To examine the importance of lipin 1 (LPIN1) gene variation in energy and glucose metabolism. Transgenic animal models have shown that lipin, a protein encoded by the LPIN1 gene, promotes fat synthesis and storage in adipose tissue while decreasing energy expenditure and lipid oxidation in skeletal muscle. Lpin1 was identified as the mutated gene in the fatty liver dystrophy mouse, which exhibits lipin...

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Source

Identifiers

PMID: 18070763
DOI: 10.1038/oby.2007.324

Genes

LPIN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of lipin 1 gene polymorphisms with measures of energy and glucose metabolism.PMID 18070763Read ↗

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