Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes.

European journal of endocrinology - 1 Jul 2010

Burgdorf Kristoffer Sølvsten, Sandholt Camilla Helene, Sparsø Thomas, Andersen Gitte, Witte Daniel R, Jørgensen Torben, Sandbaek Anelli, Lauritzen Torsten, Sørensen Thorkild I A, Madsbad Sten, Hansen Torben, Pedersen Oluf

Abstract excerpt

OBJECTIVE: Lipin-1, encoded by LPIN1, is expressed in the major metabolically active tissues. Decreased expression of lipin-1 in adipose tissue correlates with increased insulin resistance, and tagging of the LPIN1 locus has shown that rs33997857, rs6744682, and rs6708316 associate with metabolic phenotypes, specifically body mass index (BMI) and fasting serum lipid levels, both on the individual...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Mass Index
Share to Denmark
Share to Diabetes Mellitus, Type 2
Share to Nuclear Proteins
Share to Obesity
Share to Phosphatidate Phosphatase
Share to Waist Circumference
Share to White People

Source

Identifiers

PMID: 20356931
DOI: 10.1530/EJE-10-0068

Genes

LPIN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes.PMID 20356931Read ↗

Genetic variants within the LPIN1 gene, encoding lipin, are influencing phenotypes of the metabolic syndrome in humans.Semantic proximity Read ↗

The associations of LPIN1 gene expression in adipose tissue with metabolic phenotypes in the Chinese population.Semantic proximity Read ↗

Implications of central obesity-related variants in LYPLAL1, NRXN3, MSRA, and TFAP2B on quantitative metabolic traits in adult Danes.Semantic proximity Read ↗

LPIN2 is associated with type 2 diabetes, glucose metabolism, and body composition.Semantic proximity Read ↗

Genetic variants of LPIN1 indicate an association with Type 2 diabetes mellitus in a Chinese population.Semantic proximity Read ↗

Evaluating the role of LPIN1 variation in insulin resistance, body weight, and human lipodystrophy in U.K. Populations.Semantic proximity Read ↗

Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes.Semantic proximity Read ↗

Genetic variation at the perilipin (PLIN) locus is associated with obesity-related phenotypes in White women.Semantic proximity Read ↗

Common variations in perilipin gene, central obesity, and risk of type 2 diabetes in US women.Semantic proximity Read ↗

Association of lipin 1 gene polymorphisms with measures of energy and glucose metabolism.Semantic proximity Read ↗

LPL, FNDC5 and PPARγ gene polymorphisms related to body composition parameters and lipid metabolic profile in adolescents from Southern Italy.Semantic proximity Read ↗

A functional variant in the exon 5 of PLIN1 reduces risk of central obesity by possible regulation of lipid storage.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.