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Article

Genetic variants within the LPIN1 gene, encoding lipin, are influencing phenotypes of the metabolic syndrome in humans.

Diabetes - 1 Jan 2008

Wiedmann Silke, Fischer Marcus, Koehler Martina, Neureuther Katharina, Riegger Guenter, Doering Angela, Schunkert Heribert, Hengstenberg Christian, Baessler Andrea

Abstract excerpt

OBJECTIVE: Lipin, a novel molecular protein expressed by adipocytes, has marked effects on adipose tissue mass, insulin sensitivity, and glucose homeostasis. Thus, we hypothesized that genetic variants within LPIN1 are associated with traits of the metabolic syndrome. RESEARCH DESIGN AND METHODS: A total of 15 single nucleotide polymorphisms (SNPs) covering the LPIN1 gene region were genotyped in an age- and...

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Source

Identifiers

PMID: 17940119
DOI: 10.2337/db07-0083

Genes

LPIN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variants within the LPIN1 gene, encoding lipin, are influencing phenotypes of the metabolic syndrome in humans.PMID 17940119Read ↗

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