Article
The fat and thin of lipin.
Cell metabolism - 1 Jan 2005
Reitman Marc L
Abstract excerpt
Mutations in the Lpin1 gene (encoding lipin) cause the lipodystrophy (adipose tissue deficiency) of the fld mouse, but the underlying mechanism has been unclear. In this issue of Cell Metabolism, Phan and Reue (2005) show that overexpression of lipin in either muscle or adipose tissue increases adiposity. Interestingly, mice overexpressing lipin in muscle are insulin resistant, while those overexpressing lipin in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
