Article
The associations of LPIN1 gene expression in adipose tissue with metabolic phenotypes in the Chinese population.
Obesity (Silver Spring, Md.) - 1 Jan 2010
Chang Yi-Cheng, Chang Ling-Yin, Chang Tien-Jyun, Jiang Yi-Der, Lee Kuan-Ching, Kuo Shan-Shan, Lee Wei-Jei, Chuang Lee-Ming
Abstract excerpt
The LPIN1 gene, encoding lipin-1 protein, plays critical roles in adipocyte differentiation and lipid metabolism. This study aimed to analyze the association of LPIN1 mRNA levels in human adipose tissue with metabolic phenotypes. We also examined the association of LPIN1 genetic variation with type 2 diabetes and related metabolic phenotypes in the Chinese population. The relative LPIN1 mRNA levels were measured...
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