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Article

Cross-species analyses implicate Lipin 1 involvement in human glucose metabolism.

Human molecular genetics - 1 Feb 2006

Suviolahti Elina, Reue Karen, Cantor Rita M, Phan Jack, Gentile Massimiliano, Naukkarinen Jussi, Soro-Paavonen Aino, Oksanen Laura, Kaprio Jaakko, Rissanen Aila, Salomaa Veikko, Kontula Kimmo, Taskinen Marja-Riitta, Pajukanta Päivi, Peltonen Leena

Abstract excerpt

Recent studies in the mouse have demonstrated that variations in lipin expression levels in adipose tissue have marked effects on adipose tissue mass and insulin sensitivity. In the mouse, lipin deficiency prevents normal adipose tissue development, resulting in lipodystrophy and insulin resistance, whereas excess lipin levels promote fat accumulation and insulin sensitivity. Here, we investigated the effects of...

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Source

Identifiers

PMID: 16357106
DOI: 10.1093/hmg/ddi448

Genes

LPIN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cross-species analyses implicate Lipin 1 involvement in human glucose metabolism.PMID 16357106Read ↗

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