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Article

GSTO and AS3MT genetic polymorphisms and differences in urinary arsenic concentrations among residents in Bangladesh.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 May 2012

Rodrigues Ema G, Kile Molly, Hoffman Elaine, Quamruzzaman Quazi, Rahman Mahmuder, Mahiuddin Golam, Hsueh Yumei, Christiani David C

Abstract excerpt

We determined whether single nucleotide polymorphisms (SNPs) in the glutathione S-transferase omega (GSTO) and arsenic(III)methyltransferase (AS3MT) genes were associated with concentrations of urinary arsenic metabolites among 900 individuals without skin lesions in Bangladesh. Four SNPs were assessed in these genes. A pathway analysis evaluated the association between urinary arsenic metabolites and SNPs. GSTO1...

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Identifiers

PMID: 22339537
DOI: 10.3109/1354750X.2012.658863
PMCID: PMC3340466

Genes

GSTO1

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