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Article

Drosophila ESC-like can substitute for ESC and becomes required for Polycomb silencing if ESC is absent.

Developmental biology - 1 Jan 2008

Kurzhals Rebeccah L, Tie Feng, Stratton Carl A, Harte Peter J

Abstract excerpt

The Drosophila esc-like gene (escl) encodes a protein very similar to ESC. Like ESC, ESCL binds directly to the E(Z) histone methyltransferase via its WD region. In contrast to ESC, which is present at highest levels during embryogenesis and low levels thereafter, ESCL is continuously present throughout development and in adults. ESC/E(Z) complexes are present at high levels mainly during embryogenesis but...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18048023
DOI: 10.1016/j.ydbio.2007.10.025
PMCID: PMC2266587

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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