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Article

Subunit contributions to histone methyltransferase activities of fly and worm polycomb group complexes.

Molecular and cellular biology - 1 Aug 2005

Ketel Carrie S, Andersen Erica F, Vargas Marcus L, Suh Jinkyo, Strome Susan, Simon Jeffrey A

Abstract excerpt

The ESC-E(Z) complex of Drosophila melanogaster Polycomb group (PcG) repressors is a histone H3 methyltransferase (HMTase). This complex silences fly Hox genes, and related HMTases control germ line development in worms, flowering in plants, and X inactivation in mammals. The fly complex contains a catalytic SET domain subunit, E(Z), plus three noncatalytic subunits, SU(Z)12, ESC, and NURF-55. The four-subunit...

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Identifiers

PMID: 16055700
DOI: 10.1128/MCB.25.16.6857-6868.2005
PMCID: PMC1190254

Genes

SET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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