Article
A histone mutant reproduces the phenotype caused by loss of histone-modifying factor Polycomb.
Science (New York, N.Y.) - 8 Feb 2013
Pengelly Ana Raquel, Copur Ömer, Jäckle Herbert, Herzig Alf, Müller Jürg
Abstract excerpt
Although many metazoan enzymes that add or remove specific modifications on histone proteins are essential transcriptional regulators, the functional significance of posttranslational modifications on histone proteins is not well understood. Here, we show in Drosophila that a point mutation in ly...
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