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Article

Polycomb group proteins ESC and E(Z) are present in multiple distinct complexes that undergo dynamic changes during development.

Genesis (New York, N.Y. : 2000) - 1 Feb 2003

Furuyama Takehito, Tie Feng, Harte Peter J

Abstract excerpt

The Polycomb Group proteins are required for stable long-term maintenance of transcriptionally repressed states. Two distinct Polycomb Group complexes have been identified, a 2-MDa PRC1 complex and a 600-kDa complex containing the ESC and E(Z) proteins together with the histone deacetylase RPD3 and the histone-binding protein p55. We report here that there are at least two embryonic ESC/E(Z) complexes that...

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Source

Identifiers

PMID: 12533794
DOI: 10.1002/gene.10173

Genes

PRC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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