Article
A 1-megadalton ESC/E(Z) complex from Drosophila that contains polycomblike and RPD3.
Molecular and cellular biology - 1 May 2003
Tie Feng, Prasad-Sinha Jayashree, Birve Anna, Rasmuson-Lestander Asa, Harte Peter J
Abstract excerpt
Polycomb group (PcG) proteins are required to maintain stable repression of the homeotic genes and others throughout development. The PcG proteins ESC and E(Z) are present in a prominent 600-kDa complex as well as in a number of higher-molecular-mass complexes. Here we identify and characterize a 1-MDa ESC/E(Z) complex that is distinguished from the 600-kDa complex by the presence of the PcG protein Polycomblike...
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