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Article

Restriction endonuclease inhibitor IPI* of bacteriophage T4: a novel structure for a dedicated target.

Journal of molecular biology - 18 Jan 2008

Rifat Dalin, Wright Nathan T, Varney Kristen M, Weber David J, Black Lindsay W

Abstract excerpt

Phage T4 protects its DNA from the two-gene-encoded gmrS/gmrD (glucose-modified hydroxymethylcytosine restriction endonuclease) CT of pathogenic Escherichia coli, CT596, by injecting several hundred copies of the 76-amino-acid-residue nuclease inhibitor, IPI*, into the infected host. Here, the three-dimensional solution structure of mature IPI* is reported as determined by nuclear magnetic resonance techniques...

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Identifiers

PMID: 18037438
DOI: 10.1016/j.jmb.2007.10.064
PMCID: PMC2255585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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