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Article

CdiA from Enterobacter cloacae delivers a toxic ribosomal RNase into target bacteria.

Structure (London, England : 1993) - 6 May 2014

Beck Christina M, Morse Robert P, Cunningham David A, Iniguez Angelina, Low David A, Goulding Celia W, Hayes Christopher S

Abstract excerpt

Contact-dependent growth inhibition (CDI) is one mechanism of inter-bacterial competition. CDI(+) cells export large CdiA effector proteins, which carry a variety of C-terminal toxin domains (CdiA-CT). CdiA-CT toxins are specifically neutralized by cognate CdiI immunity proteins to protect toxin-producing cells from autoinhibition. Here, we use structure determination to elucidate the activity of a CDI toxin from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24657090
DOI: 10.1016/j.str.2014.02.012
PMCID: PMC4016183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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