Article

Insights into Genome Ejection by a Therapeutic phiKMV-like Bacteriophage

2026-05-19

Abstract excerpt

<h4>ABSTRACT</h4> Ar-KM is a phiKMV-like therapeutic bacteriophage used in clinical candidate phage therapy cocktails to treat lung infections caused by Pseudomonas aeruginosa. Here, we present an integrative structural atlas of Ar-KM proteins using cryo-EM, proteomics, and bioinformatics. From a single purified Ar-KM preparation, we identified three distinct populations: mature DNA-filled virions, open-nozzle pa...

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Literature Corpus work: 6ad505d1-f1c4-59ba-927f-d7bce60b08c0
DOI: 10.64898/2026.05.18.726046

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