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Article

Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 allele.

Molecular and cellular biology - 1 Sept 2006

Huang Xinyan, Fu Ying, Charbeneau Raelene A, Saunders Thomas L, Taylor Douglas K, Hankenson Kurt D, Russell Mark W, D'Alecy Louis G, Neubig Richard R

Abstract excerpt

Signal transduction via guanine nucleotide binding proteins (G proteins) is involved in cardiovascular, neural, endocrine, and immune cell function. Regulators of G protein signaling (RGS proteins) speed the turn-off of G protein signals and inhibit signal transduction, but the in vivo roles of RGS proteins remain poorly defined. To overcome the redundancy of RGS functions and reveal the total contribution of RGS...

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Identifiers

PMID: 16943428
DOI: 10.1128/MCB.00314-06
PMCID: PMC1592866

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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