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Article

RGS-Insensitive G Proteins as In Vivo Probes of RGS Function.

Progress in molecular biology and translational science - 1 Jan 2015

Neubig Richard R

Abstract excerpt

Guanine nucleotide-binding proteins of the inhibitory (Gi/o) class play critical physiological roles and the receptors that activate them are important therapeutic targets (e.g., mu opioid, serotonin 5HT1a, etc.). Gi/o proteins are negatively regulated by regulator of G protein signaling (RGS) proteins. The redundant actions of the 20 different RGS family members have made it difficult to establish their overall...

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PMID: 26123300
DOI: 10.1016/bs.pmbts.2015.04.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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