Article
Studies on RNA-protein interactions and enzyme activity by mutational analysis of telomerase.
Nucleic acids symposium series (2004) - 1 Jan 2007
Ohsako Yoshihisa, Tsutsumi Kota, Li Xianglan, Kurihara Yasuyuki, Uesugi Seiichi
Abstract excerpt
The protein component of telomerase (TERT: telomerase reverse transcriptase) contains a domain (RID2: RNA interaction domain 2), which interacts with the RNA component of telomerase (TR: telomerase RNA). RID2 includes a telomerase-specific motif (T-motif), which is highly conserved among species. But, the role of T-motif is not clearly understood. To elucidate the role of T-motif in the telomerase activity and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
