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Article

Structure, interactions and effects on activity of the 5'-terminal region of human telomerase RNA.

Journal of biochemistry - 1 May 2007

Li Xianglan, Nishizuka Hidetoshi, Tsutsumi Kota, Imai Yuka, Kurihara Yasuyuki, Uesugi Seiichi

Abstract excerpt

Telomerase is an enzyme that catalyzes addition of telomeric repeat sequences to the 3'-termini of eukaryotic chromosome DNA. The catalytic core of telomerase consists of a protein component, telomerase reverse transcriptase (TERT), for the catalysis and an RNA component, telomerase RNA (TR), containing the template for the sequence. Human telomerase RNA (hTR) consists of 451 nucleotides (nt) and contains...

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Identifiers

PMID: 17387120
DOI: 10.1093/jb/mvm081

Genes

TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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