Back to search

Article

Development and characterization of polyclonal antibodies against the linker region of the telomere-binding protein TRF2

2018-03-01

Abstract excerpt

TRF2 (telomeric repeat binding factor 2) is an essential component of the telomere-binding protein complex shelterin. TRF2 induces the formation of a special structure of telomeric DNA and counteracts activation of DNA damage-response pathways telomeres. TRF2 has a poorly characterized linker region (udTRF2) between its homodimerization and DNA-binding domains. Some lines of evidence have shown that this region co...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
76f0a2b6-abe2-54e5-af8a-60d50de3ebdd
DOI
10.1016/j.ejbt.2017.12.001
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Development and characterization of polyclonal antibodies against the linker region of the telomere-binding protein TRF2DOI 10.1016/j.ejbt.2017.12.001
Structure of the TRFH Dimerization Domain of the Human Telomeric Proteins TRF1 and TRF2Semantic proximity
TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres.Semantic proximity
The Intra- and Extra-Telomeric Role of TRF2 in the DNA Damage ResponseSemantic proximity
Telomere Repeat Binding Factor 2 Interacts with Base Excision Repair Proteins and Stimulates DNA Synthesis by DNA Polymerase βSemantic proximity
TIN2 Mediates Functions of TRF2 at Human TelomeresSemantic proximity
Human telomeres contain two distinct Myb–related proteins, TRF1 and TRF2Semantic proximity
Telomeric localization of TRF2, a novel human telobox proteinSemantic proximity
How the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high‐resolution crystal structuresSemantic proximity
Comparison between TRF2 and TRF1 of their telomeric DNA-bound structures and DNA-binding activities.Semantic proximity
Human Rap1 Interacts Directly with Telomeric DNA and Regulates TRF2 Localization at the TelomereSemantic proximity
Human Rap1 modulates TRF2 attraction to telomeric DNASemantic proximity
Interaction of human Ku70 with TRF2Semantic proximity
Select a neighboring publication to make it the new centre.