Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNA Binding Domain of Telomerase Reverse Transcriptase

1 Feb 2001

Abstract excerpt

Telomerase is a ribonucleoprotein reverse transcriptase that extends the ends of chromosomes. The two telomerase subunits essential for catalysis in vitro are the telomerase reverse transcriptase (TERT) and the telomerase RNA. Using truncations and site-specific mutations, we identified sequence elements of TERT and telomerase RNA required for catalytic activity and protein-RNA interaction for Tetrahymena...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced biosensing and bioanalysis techniques
Share to Chromosomal and Genetic Variations
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11158287
DOI: 10.1128/mcb.21.4.990-1000.2001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNA Binding Domain of Telomerase Reverse TranscriptasePMID 11158287Read ↗

Structure and function of telomerase RNA.Semantic proximity Read ↗

A conserved motif in Tetrahymena thermophila telomerase reverse transcriptase is proximal to the RNA template and is essential for boundary definition.Semantic proximity Read ↗

Identification of an essential proximal sequence element in the promoter of the telomerase RNA gene of Tetrahymena thermophila.Semantic proximity Read ↗

Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase.Semantic proximity Read ↗

InTERTpreting telomerase structure and functionSemantic proximity Read ↗

The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity.Semantic proximity Read ↗

A structurally conserved human and Tetrahymena telomerase catalytic coreSemantic proximity Read ↗

Molecular and Evolutionary Analysis of RNA–Protein Interactions in Telomerase RegulationSemantic proximity Read ↗

The telomerase database.Semantic proximity Read ↗

A new telomerase RNA element that is critical for telomere elongation.Semantic proximity Read ↗

Functional multimerization of human telomerase requires an RNA interaction domain in the N terminus of the catalytic subunit.Semantic proximity Read ↗

It all comes together at the ends: telomerase structure, function, and biogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.